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Home » CPAP Machines » BiPAP/VPAP/BiLevel » DS650HS, DS650S

PR System One DS650 REMstar BiPAP Pro with humidifier
Model: DS650HS, DS650S

PR System One DS650 REMstar BiPAP Pro with humidifier
Click to enlarge

This machine has been discontinued. To see the newest model, please look at the Respironics DS660 BiPAP Pro.

Respironics PR System One DS650 REMstar BiPAP Pro with humidifier

Respironics aims to take a more intelligent path towards the complete sleep management cycle by utilizing cutting edge technology to deliver the best results. System One Resistance and Humidity control work together to ensure ideal humidity levels and pressure relief suited to your individual needs. Dry Box technology aims to actively protect your device from water damage, ensuring the longevity of your sleep therapy management system. You can rest easy knowing Respironics technology works harder so you don't have to.

Enhanced System One Humidity Control with Dry Box Technology

System One provides excellent control of humidity settings designed to provide you with the customization you desire. This device adapts to surrounding temperatures and relative humidity, which provides you with optimal conditions at all times. Dry Box works to ensure the water source is separated from the electronics inside the device in order to eliminate the risk of spills, and subsequent water damage.

System One Resistance Control

Respironics resistance control provides exceptional user comfort and is paired with great versatility. A numbering system on all Respironic CPAP masks identifies and defines the resistance characteristics of each mask, allowing the BiPAP to adapt easily. System One is able to automatically adapt for a variety of resistances, making it compatible with all mask types. This guarantees synchronization between the mask and device ensuring optimal pressure is maintained at all points in time. You can be assured that you will be getting maximum comfort and the ideal pressure throughout the night.

Flex Family Technologies

Bi-Flex technology analyzes every breath in order to deliver unmatched pressure relief when needed during inhalation and exhalation. This translates into a more natural breathing experience for you and provides you with optimal comfort.

Advanced Event Detection

REMstar utilizes Digital Auto-Trak Sensitivity to identify conditions beyond classic OSA. This intelligent algorithm monitors breathing patterns and adapts to abnormal pressure changes, and provides actionable data to identify other conditions. You and your healthcare provider can utilize this data to improve upon therapy, while receiving exceptional sleep therapy.

Key Features

  • Superior Monitoring through Advanced Event Detection
  • System One Humidity and Resistance Control
  • Dry Box Technology
Reviewers Tip:

This device includes Respironics' latest ramp technology.

This item is discontinued


What are the modes on this device?

Bi-level Spontaneous Bi-Flex.

What kind filters does this device use?

Reusable Pollen, or optional ultra fine.

What is the pressure range?

For IPAP the pressure range is from 3cm to 20cm H20 for EPAP 3cm to 20cm H20.

RX Required.

SKU: 96
HCPCS CPAP Code(s): E0470 (BiPAP), E0562(humidifier)

Product Specifications


Bi-level Spontaneous Bi-Flex

Pressure Range:

IPAP: 3 cm H2O to 20 cm H2O
EPAP: 3 cm H2O to 20 cm H2O

Ramp Time :

0 to 45 min. (5-min. increments)

Ramp Activation:

Unlimited number of ramps per night

Starting Ramp Pressure:

3 cm H2O to EPAP level

BiPAP Dimensions:

11.4" L x 7.0" W x 5.5" H


5.75 lbs (2.6 kg)


Reusable Pollen, Optional Ultra Fine


On-board keypad

Therapy Memory

6 months @ 3 usage sessions/day; 7 days in-depth data analysis. Date, time, duration at pressure, patient event histograms, short-term detailed events, long-term trends, FOSQ tests and SmartCard


Pressure Setting, Data/Time of each use, duration at Pressure

Compliance Meter

LCD: Total Operation Time and Time at Pressure

Data DS Card:


Pressure Relief on Exhale:

Yes, Flex Family

Auto Altitude Compensation:


Electrical Requirements:

100 240 VAC, 12 DC

Battery Operation:



Integrated Heated Humidifier


2-Year Manufacturer Warranty

DC Power:

Direct-connect cord

Manufacturer's Website:
  • Respironics PR System one REMStar BiPAP Pro CPAP Machine with Bi-Flex
  • Travel Bag
  • System One Heated Humidifier
  • User Manual
  • Performance Tubing only
  • Power Adapter (auto adaptive 100v-240v AC)
  • Free Filters for 3 years (only from Respshop)
  • Smart Card
  • by Shery C Date Added: Wednesday 30 April, 2014
    Very bad quality.Very bad quality.Very bad quality.I will not go to this website anymore. They are not professional. They send me the wrong product and donot take back. It is really back experience. Not happy for their service.

    Rating: 1 of 5 Stars! [1 of 5 Stars!]
    by Deborah B Date Added: Friday 22 June, 2012
    This was the second unit i purchased. Much better then my first one, and very impressed with its options and functions!

    Rating: 5 of 5 Stars! [5 of 5 Stars!]
    Displaying 1 to 2 (of 2 reviews) Result Pages:  1